Hurem S, Gomes T, Brede DA, Mayer I, Lobert VH, Mutoloki S, Gutzkow KB, Teien HC, Oughton D, Aleström P, Lyche JL. Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects. Ecotoxicol Environ Saf. 2018 Feb 13;154:19-26. doi: 10.1016/j.ecoenv.2018.02.031. [Epub ahead of print] PMID: 29453161

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O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE. Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation. Nat Cell Biol. 2017 Oct 30. doi: 10.1038/ncb3631.

In the news: Cellular context determines whether factor promotes or tamps down cancer, PNAS

Trafikkaos i celler fører til tumorvekst, University of Oslo Website, Medical Faculty (in Norwegian)

Dobbeltagent i kroppens celler får svulster til å vokse, Kreftforeningen Website (in Norwegian)

Researchers discover how traffic jam in intracellular sorting can cause tumor development, The Medical News

Cancer research – how a traffic jam causes tumor growth, Medical Xpress

Cancer research – how a traffic jam causes tumor growth, AlphaGalileo

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Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A. HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889.

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Halsne R, Tandberg JI, Lobert VH, Østby GC, Thoen E, Ropstad E, Verhaegen S. Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro. Toxicol Lett. 2016 Aug 7;259:95-107. doi: 10.1016/j.toxlet.2016.08.004.

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Lobert VH, Mouradov D, Heath JK. Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer. Adv Exp Med Biol. 2016;916:411-37. doi: 10.1007/978-3-319-30654-4_18. Book Chapter part of the 'Cancer and Zebrafish, Mechanisms, Techniques and Models' edited by David Langenau.

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Griffiths GW, Müller F, Ledin J, Patton EE, Gjøen T, Lobert VH, Winther-Larsen HC, Mullins M, Joly JS, Weltzien FA, Press CM, Aleström P. Fish from Head to Tail: The 9th European Zebrafish Meeting in Oslo. Zebrafish. 2016 Apr;13(2):132-7.

 

Oppelt A, Haugsten EM, Zech T, Danielsen HE, Sveen A, Lobert VH, Skotheim RI, Wesche J. PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochem J. 2014 Aug 1;461(3):383-90.

 

Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C. Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin. EMBO Rep. 2013 Jan;14(1):10-1.

 

Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J. Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. EMBO Rep. 2013 Jan;14(1):57-64. 

 

Lobert VH, Stenmark H. The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain. J Cell Sci. 2012 Jan 1;125(Pt 1):29-36.

 

Lobert VH, Stenmark H. Cell polarity and migration: emerging role for the endosomal sorting machinery. Physiology (Bethesda). 2011 Jun;26(3):171-80.

 

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H. Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting. Traffic. 2011 Sep;12(9):1211-26.

 

Lobert VH, Stenmark H. Ubiquitination of α-integrin cytoplasmic tails. Commun Integr Biol. 2010 Nov;3(6):583-5.

 

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H. Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes. Dev Cell. 2010 Jul 20;19(1):148-59.

 

Kaarbø M, Mikkelsen OL, Malerød L, Qu S, Lobert VH, Akgul G, Halvorsen T, Maelandsmo GM, Saatcioglu F. PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells. Cell Oncol. 2010;32(1-2):11-27.

 

Rodahl LM, Stuffers S, Lobert VH, Stenmark H. The role of ESCRT proteins in attenuation of cell signalling. Biochem Soc Trans. 2009 Feb;37(Pt 1):137-42.